Karolina Wojtowicz

Graduates // Karolina Wojtowicz

Information:

2002-2003 Master's thesis:  “Oxidative stress in Saccharomyces cerevisiae strains overexpressing ABC pumps and deletions of genes superoxide dismutases - the protective function of natural antioxidants”

Supervisor:  dr. hab. eng.  Marcin Łukaszewicz

About:

The thesis examined and compared the phenotypes of Saccharomyces cerevisiae resulting from deletion of  SOD1 or SOD2 individually and  SOD1 , SOD2 genes altogether. Methods for differentiating strains tested as well as experimental conditions, allowing efficient testing of various substances that affect the observed phenotypes were developed. The influence on phenotypes of (flavonoids, carotenoids) and vitamins was tested.
Publications

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Author Title Date  
Anna Krasowska
Dorota Dziadkowiec
Marcin Łukaszewicz
Karolina Wojtowicz
Marcin Łukaszewicz		 Effect of antioxidants on Saccharomyces cerevisiae mutants deficient in superoxide dismutases 2003 ReadExport
Anna Krasowska
Dorota Dziadkowiec
Marcin Łukaszewicz
Karolina Staniczek
Karolina Wojtowicz		 The supression by natural antioxidants of oxygen sensitivity in yeast strains lacking mitrochondrial and cytoplasmic superoxide dismutases 2002 ReadExport

  • Biosurfactants

    We identified chemical structures of newly isolated biosurfactants which are secreted by Arctic microorganisms. We are investigating their antibacterial, antifungal properties as well as proapoptotic activity. Biosurfactants can be used as an antiseptics.

  • Biogas

    We are investigating and optimizing the efficiency of metanogenesis in bioreactors. We are also testing various substrates (industrial waste) as materials for biogas production. Microorganisms which participate in this process are investigated as e.g. biofilm producers.

  • Bacteriophages

    Bacteriophages or phages are bacterial viruses. We isolated and are now investigating phages which kill Bacillus strains. Beside the basic research, the collection of phages can be used in industry as for example eliminators of infections.

  • Antiseptics

    Fungal infections are difficult to treat because of the small number of effective drugs. Candida albicans resistance depends on the activity of ABC transporters (MDR, CDR). We have investigated strains and methods for finding new antifungal compounds (synthetic and natural) e.g. probiotic yeast Saccharomyces boulardii.