Dorota Gapa
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Information: 2001-2002 Master's thesis: “Characterization of changes in the yeast cell membrane under oxidative stress” Supervisor: Dr. Anna Krasowska 2000 Bachelor: “Theories about the process of cell aging” Supervisor: Dr. Anna Krasowska |
About: The thesis determined resistance of selected yeast strains to oxidative stress induced with compounds of varying hydrophilicity. Composition of plasmalema lipids was compared for the tested yeast strains. The method for the determination of conjugated dienes formation in lipids, isolated from yeast cell membranes, was improved. The susceptibility of yeast membrane lipids from various strains was evaluated, using improved measuring of the conjugated dienes. |
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Biosurfactants
We identified chemical structures of newly isolated biosurfactants which are secreted by Arctic microorganisms. We are investigating their antibacterial, antifungal properties as well as proapoptotic activity. Biosurfactants can be used as an antiseptics.
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Biogas
We are investigating and optimizing the efficiency of metanogenesis in bioreactors. We are also testing various substrates (industrial waste) as materials for biogas production. Microorganisms which participate in this process are investigated as e.g. biofilm producers.
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Bacteriophages
Bacteriophages or phages are bacterial viruses. We isolated and are now investigating phages which kill Bacillus strains. Beside the basic research, the collection of phages can be used in industry as for example eliminators of infections.
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Antiseptics
Fungal infections are difficult to treat because of the small number of effective drugs. Candida albicans resistance depends on the activity of ABC transporters (MDR, CDR). We have investigated strains and methods for finding new antifungal compounds (synthetic and natural) e.g. probiotic yeast Saccharomyces boulardii.