Dr. Dorota Dziadkowiec

Staff // Dorota Dziadkowiec

Information:

Research topics:

1. Identification and characterisation of new regulators of DNA repair in Schizosaccharomyces pombe and Saccharomyces cerevisiae

publications:

  1. M. Cal-Bąkowska, I. Litwin, T. Bocer, R. Wysocki, D. Dziadkowiec (2011) The Swi2-Snf2-like protein Uls1 is involved in replication stress response. Nucleic Acids Research 39: 8765-8777.
  2. C. Tapia-Alveal, E. A. Outwin, N. Trempolec, D. Dziadkowiec , J. M. Murray and M. J. O'Connell (2010): SMC complexes and topoisomerase II work together so that sister chromatids can work apart. Cell Cycle 9: 2065-2070.
  3. D. Dziadkowiec, E. Petters, A. Dyjankiewicz, P. Karpiński, V. Garcia, A. Watson, A.M. Carr (2009) The role of novel genes rrp1+ and rrp2+ in the repair of DNA damage in Schizosaccharomyces pombe. DNA Repair 8: 627-636.
  4. P. Karpiński, D. Dziadkowiec (2004): Nowopoznane bakteryjne polimerazy DNA i ich rola w tolerancji uszkodzeń genomu. Postępy Biochemii  50: 209-217.
  5. Y. Akamatsu, D. Dziadkowiec, M. Ikeguchi, H. Shinagawa, H. Iwasaki (2003): Two different Swi5-containing complexes are involved in mating-type switching and recombination repair in fission yeast. Proc. Natl. Acad. Sci. USA 100:15770-15775.

MSc theses:

  • rad8+ paralogs in DNA repair in Schizosaccharomyces pombe. - Karol Kramarz (2011)
  • Non-canonical helicases in DNA repair in Schizosaccharomyces pombe. - Natalia Trempolec (2010)
  • The analysis of epistatic interactions between rrp1+, rrp2+  and srs2+ in DNA repair in Schizosaccharomyces pombe. - Aleksandra Jethon (2009)
  • Genetic and molecular characterisation of Schizosaccharomyces pombe strains devoid of rrp1+ and rrp2+ genes. - Edyta Petters (2007)
  • Characterisation of rrp1+ and rrp2+ genes taking part in DNA repair in Schizosaccharomyces pombe. - Michał Turniak (2007)
  • Comparison of fenotypes of Schizosaccharomyces pombe strains devoid of rrp1+ and rad8+ genes.  - Agnieszka Dyjankiewicz (2006)
  • Characterisation of Schizosaccharomyces pombe strain devoid of SPAC17A2.12 gene homologous to RIS1 (DIS1)  from Saccharomyces cerevisiae. - Paweł Karpiński (2004)

 
2. The influence of active ingredients secreted by Saccharomyces boulardii and Saccharomyces cerevisiae on virulence factors of Candida albicans.

publications:

  1.  A. Murzyn, A. Krasowska, D. Augustyniak, G. Majkowska-Skrobek, M. Łukaszewicz, D. Dziadkowiec (2010): The effect of Saccharomyces boulardii on Candida albicans infected human intestinal cell lines Caco-2 and Intestin 407. FEMS Microbiology Letters 310: 17-23
  2. A. Murzyn, A. Krasowska, P. Stefanowicz, D. Dziadkowiec, M. Łukaszewicz (2010) Capric acid secreted by S. boulardii inhibits C. albicans filamentous growth, adhesion and biofilm formation. PLos one 5: e12050
  3. A. Krasowska, A. Murzyn, A. Dyjankiewicz, M. Łukaszewicz, D. Dziadkowiec (2009) The antagonistic effect of Saccharomyces boulardii on Candida albicans filamentation, adhesion and biofilm formation. FEMS Yeast Research 9:1312-1321.


MSc theses:

  • The mechanism of action of Saccharomyces cerevisiae against adhesion and germ tube formation Candida albicans. - Sabina Kuźlak (2010)
  • The influence of Saccharomyces cerevisiae on virulence factors of Candida albicans.  - Magdalena Korczyńska (2008)


3. Reaction of Saccharomyces cerevisiae cells to stress.

publications:

  1. D. Dziadkowiec, A. Krasowska, A. Liebner, K. Sigler (2007) Protective role of mitochondrial superoxide dismutase against high osmolarity, heat and metalloid stress in Saccharomyces cerevisiae. Folia Microbiologica 52: 120-126.
  2. A. Krasowska, D. Dziadkowiec, A. Polinceusz, A. Płonka, M. Łukaszewicz (2007): Cloning of flax oleic fatty acid desaturase and its expression in yeast. JAOCS 84: 809-816.
  3. A. Krasowska, D. Dziadkowiec, M. Łukaszewicz, K. Wojtowicz, K. Sigler (2003): Effect of antioxidants on Saccharomyces cerevisiae. Folia Microbiologica 48: 754-760.
  4. R.Wysocki, S. Clemens, D. Augustyniak, P. Golik, E. Maciaszczyk, M. J. Tamas, D. Dziadkowiec (2003): Metalloid tolerance based on phytochelatins is not functionally equivalent to the arsenite transporter Acr3p. Biochemical and Biophysical Research Communications 304: 293-300.

MSc theses:

  • The influence of stress conditions on growth of Saccharomyces cerevisiae mutants devoid of superoxide dismutases.  - Anna Liebner (2004)
  • The influence of deletion of genes coding for ABC proteins on the fenotype of Saccharomyces cerevisiae mutants devoid of superoxide dismutases. - Karolina Staniczek (2003)

Other publications:

  1. C. Monteilhet, D. Dziadkowiec, T. Szczepanek, J. Lazowska (2000): Purification and characterization of the DNA cleavage and recognition site of I-ScaT mitochondrial group I intron encoded endonuclease produced in Escherichia coli. Nucleic Acids Research 28, 1245-1251.
  2. D. Dziadkowiec, L.P. Mansfield, S.J. Forsythe (1995): The detection of Salmonella in skimmed milk powder enrichments using conventional and immunomagnetic separation. Letters in Applied Microbiology 20, 361-364.
  3. T.M. Lachowicz, D. Dziadkowiec, I. Kopocińska, B. Kopociński (1995): Population dynamics in the co-culture of Shigella flexneri lb. Microbios 83, 89-106.

Teaching:

  • lectures and laboratories on General Microbiology for 2nd year Biotechnology students
  • Microbiology and health - lecture for 3rd year Biotechnology students

About:

Publications

Filter publications:  
Author Title Date  
Ireneusz Litwin
Tomasz Bocer
Dorota Dziadkowiec
Robert Wysocki
Oxidative Stress and Replication-Independent DNA Breakage Induced by Arsenic in Saccharomyces cerevisiae 2013 ReadExport
Dorota Dziadkowiec
Karol Kramarz
Karolina Kanik
Piotr Wiśniewski
Antony M. Carr
Involvement of Schizosaccharomyces pombe rrp1+ and rrp2+ in the Srs2- and Swi5/Sfr1-dependent pathway in response to DNA damage and replication inhibition 2013 ReadExport
Magdalena Cal-Bąkowska
Ireneusz Litwin
Tomasz Bocer
Robert Wysocki
Dorota Dziadkowiec
The Swi2-Snf2-like protein Uls1 is involved in replication stress response. 2011 ReadExport
Anna Murzyn
Anna Krasowska
Piotr Stefanowicz
Dorota Dziadkowiec
Marcin Łukaszewicz
Capric acid secreted by S. boulardii inhibits C. albicans filamentous growth adhesion and biofilm formation 2010 ReadExport
Dorota Dziadkowiec SMC complexes and topoisomerase II work together so that sister chromatids can work apart. 2010 ReadExport
Anna Krasowska
Anna Murzyn
Agnieszka Dyjankiewicz
Marcin Łukaszewicz
Dorota Dziadkowiec
The antagonistic effect of Saccharomyces boulardii on Candida albicans filamentation adhesion and biofilm formation 2009 ReadExport
Dorota Dziadkowiec
Edyta Rogulska (Petters)
Agnieszka Dyjankiewicz
Paweł Karpiński
The role of novel genes rrp1+ and rrp2+ in the repair of DNA damage in Schizosaccharomyces pombe 2009 ReadExport
Anna Krasowska
Dorota Dziadkowiec
Anna Mróz (Polinceusz)
Aneta Plonka
Marcin Łukaszewicz
Cloning of flax oleic fatty acid desaturase and its expression in yeast 2007 ReadExport
Dorota Dziadkowiec
Anna Krasowska
Anna Liebner
Karel Sigler
Protective role of mitochondrial superoxide dismutase against high osmolarity heat and metalloid stress inSaccharomyces cerevisiae 2007 ReadExport
Dorota Dziadkowiec
Paweł Karpiński
Nowopoznane bakteryjne polimerazy DNA i ich rola w tolerancji uszkodzeń genomu 2004 Export
Anna Krasowska
Dorota Dziadkowiec
Marcin Łukaszewicz
Karolina Wojtowicz
Marcin Łukaszewicz
Effect of antioxidants on Saccharomyces cerevisiae mutants deficient in superoxide dismutases 2003 ReadExport
Dorota Dziadkowiec Metalloid tolerance based on phytochelatins is not functionally equivalent to the arsenite transporter Acr3p 2003 ReadExport
Dorota Dziadkowiec Two different Swi5-containing complexes are involved in mating-type switching and recombination repair in fission yeast 2003 ReadExport
Anna Krasowska
Dorota Dziadkowiec
Marcin Łukaszewicz
Karolina Staniczek
Karolina Wojtowicz
The supression by natural antioxidants of oxygen sensitivity in yeast strains lacking mitrochondrial and cytoplasmic superoxide dismutases 2002 ReadExport
Dorota Dziadkowiec Purification and characterization of the DNA cleavage and recognition site of I-ScaT mitochondrial group I intron encoded endonuclease produced in Escherichia coIi 2000 Export
Dorota Dziadkowiec Population dynamics in the co-culture of Shigella flexneri lb 1995 Export
Dorota Dziadkowiec The detection of Salmonella in skimmed milk powder enrichments using conventional and immunomagnetic separation 1995 Export
  • Biosurfactants

    We identified chemical structures of newly isolated biosurfactants which are secreted by Arctic microorganisms. We are investigating their antibacterial, antifungal properties as well as proapoptotic activity. Biosurfactants can be used as an antiseptics.

  • Biogas

    We are investigating and optimizing the efficiency of metanogenesis in bioreactors. We are also testing various substrates (industrial waste) as materials for biogas production. Microorganisms which participate in this process are investigated as e.g. biofilm producers.

  • Bacteriophages

    Bacteriophages or phages are bacterial viruses. We isolated and are now investigating phages which kill Bacillus strains. Beside the basic research, the collection of phages can be used in industry as for example eliminators of infections.

  • Antiseptics

    Fungal infections are difficult to treat because of the small number of effective drugs. Candida albicans resistance depends on the activity of ABC transporters (MDR, CDR). We have investigated strains and methods for finding new antifungal compounds (synthetic and natural) e.g. probiotic yeast Saccharomyces boulardii.